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Anti-Human ATRAID Polyclonal Antibody (HD677014)

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Overview
Catalog No.HD677014
Description
Anti-Human ATRAID Polyclonal Antibody (HD677014) is a rabbit polyclonal antibody detecting ATRAID. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ATRAID (Leu31-Ser199).
Target APR-3, APR3, ATRAID, All-trans retinoic acid-induced differentiation factor, Apoptosis-related protein 3, C2orf28, p18
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6UW56
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

All-trans retinoic acid-induced differentiation factor (ATRAID) is a ~24 kDa protein. Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol.

1. Yu, Z. et al. (2018) eLife 7. PMID: 29745899
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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