

| Catalog No. | HV654014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human BAD Polyclonal Antibody (HV654014) is a rabbit polyclonal antibody detecting BAD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BAD (Phe2-Gln168). | ||||||||
| Target | Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bcl2-L-8, BAD, Bcl-2-like protein 8, BBC6, Bcl-2-binding component 6, BCL2L8, Bcl2-associated agonist of cell death, | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q92934 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Bcl2-associated agonist of cell death (BAD) is a ~18 kDa protein. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. | ||||||||
| Note | For research use only. |
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