

| Catalog No. | HP381014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BCL7B (Ser2-Thr52). | ||||||||
| Target | B-cell CLL/lymphoma 7 protein family member B, BCL7B, Hom s 3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BQE9 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | B-cell CLL/lymphoma 7 protein family member B (BCL7B) is a ~22 kDa protein. Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression. 1. Uehara, T. et al. (2015) PLoS genetics 11, e1004921. PMID: 25569233 | ||||||||
| Note | For research use only. |
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