Anti-Human BCR Recombinant Antibody (SAA1570) (HY023013)

Name: Anti-Human BCR Recombinant Antibody (SAA1570)
Brand: abinScience
SKU: HY023013
Price: 196 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY023013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1570

Clonality

Monoclonal

Target

Renal carcinoma antigen NY-REN-26, BCR1, BCR, D22S11, Breakpoint cluster region protein

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P11274

RRID

Anti-Human BCR Antibody (SAA1570) (abinScience Cat# HY023013, RRID:AB_3727331)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Breakpoint cluster region protein (BCR) is a ~142 kDa protein. Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.

1. Cho, YJ. et al. (2007) Molecular and cellular biology 27, 899-911. PMID: 17116687

2. Diekmann, D. et al. (1991) Nature 351, 400-2. PMID: 1903516

3. Chuang, TH. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 10282-6. PMID: 7479768

4. Dubash, AD. et al. (2013) The Journal of cell biology 202, 653-66. PMID: 23940119

5. Maru, Y. et al. (1991) Cell 67, 459-68. PMID: 1657398

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human BCR Antibody (SAA1570)

References

Datasheet

Anti-Human BCR Recombinant Antibody (SAA1570).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human BCR Recombinant Antibody (SAA1570) (HY023013)

Overview

Images

References

Datasheet

SDS

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