

| Catalog No. | HP802014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human BLOC1S6 Polyclonal Antibody (HP802014) is a rabbit polyclonal antibody detecting BLOC1S6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human BLOC1S6 (Asp46-Met172). | ||||||||
| Target | Biogenesis of lysosome-related organelles complex 1 subunit 6, PA, Pallid protein homolog, PLDN, BLOC1S6, Syntaxin 13-interacting protein, Pallidin, BLOC-1 subunit 6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UL45 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC1S6) is a ~19 kDa protein. Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. | ||||||||
| Note | For research use only. |
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