Anti-Human BMP1 Recombinant Antibody (SAA1793) (HY077013)

Name: Anti-Human BMP1 Recombinant Antibody (SAA1793)
Brand: abinScience
SKU: HY077013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HY077013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1793

Clonality

Monoclonal

Target

PCOLC, Mammalian tolloid protein, mTld, Bone morphogenetic protein 1, PCP, BMP-1, Procollagen C-proteinase, BMP1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13497

RRID

Anti-Human BMP1 Antibody (SAA1793) (abinScience Cat# HY077013, RRID:AB_3727555)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.

1. N'Diaye, EN. et al. (2021) American journal of physiology. Cell physiology 320, C162-C174. PMID: 33206546

2. Anastasi, C. et al. (2020) Science signaling 13. PMID: 32636307

3. Wang, J. et al. (2021) Journal of periodontology 92, 1018-1029. PMID: 33169406

4. Rosell-García, T. et al. (2019) The Journal of biological chemistry 294, 11087-11100. PMID: 31152061

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human BMP1 Antibody (SAA1793)

References

Datasheet

Anti-Human BMP1 Recombinant Antibody (SAA1793).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human BMP1 Recombinant Antibody (SAA1793) (HY077013)

Overview

Images

References

Datasheet

SDS

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