Anti-Human BMPR2 Recombinant Antibody (SAA1802) (HC650013)

Name: Anti-Human BMPR2 Recombinant Antibody (SAA1802)
Brand: abinScience
SKU: HC650013
Price: 196 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC650013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1802

Clonality

Monoclonal

Target

BMP type II receptor, BMPR-II, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, BMPR2, PPH1, BMP type-2 receptor, BMPR-2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13873

RRID

Anti-Human BMPR2 Antibody (SAA1802) (abinScience Cat# HC650013, RRID:AB_3727564)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Bone morphogenetic protein receptor type-2 (BMPR2) is a ~115 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs.

1. Rudarakanchana, N. et al. (2002) Human molecular genetics 11, 1517-25. PMID: 12045205

2. Rejon, CA. et al. (2013) Cellular signalling 25, 2717-26. PMID: 24018044

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human BMPR2 Antibody (SAA1802)

References

Datasheet

Anti-Human BMPR2 Recombinant Antibody (SAA1802).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human BMPR2 Recombinant Antibody (SAA1802) (HC650013)

Overview

Images

References

Datasheet

SDS

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