Anti-Human BPIFA1/LunX Recombinant Antibody (SAA1910) (HA021013)

Name: Anti-Human BPIFA1/LunX Recombinant Antibody (SAA1910)
Brand: abinScience
SKU: HA021013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HA021013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1910

Clonality

Monoclonal

Target

Von Ebner protein Hl, SPLUNC1, Palate lung and nasal epithelium clone protein, PLUNC, SPURT, Lung-specific protein X, Tracheal epithelium-enriched protein, BPI fold-containing family A member 1, BPIFA1, Secretory protein in upper respiratory tracts, Nasopharyngeal carcinoma-related protein, LUNX, Short PLUNC1, NASG

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NP55

RRID

Anti-Human BPIFA1/LunX Antibody (SAA1910) (abinScience Cat# HA021013, RRID:AB_3727674)
_x005F_x005F_x000D_

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

BPI fold-containing family A member 1 (BPIFA1/LunX) is a ~26 kDa protein. Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants.

1. Ning, F. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 5349-60. PMID: 25223608

2. Sayeed, S. et al. (2013) Infection and immunity 81, 285-91. PMID: 23132494

3. Liu, Y. et al. (2013) The American journal of pathology 182, 1519-31. PMID: 23499554

4. Walton, WG. et al. (2016) Biochemistry 55, 2979-91. PMID: 27145151

5. Garland, AL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15973-8. PMID: 24043776

6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190

7. Lindahl, M. et al. (2001) Electrophoresis 22, 1795-800. PMID: 11425234

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human BPIFA1/LunX Antibody (SAA1910)

References

Datasheet

Anti-Human BPIFA1/LunX Recombinant Antibody (SAA1910).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human BPIFA1/LunX Recombinant Antibody (SAA1910) (HA021013)

Overview

Images

References

Datasheet

SDS

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