Anti-Human BPNT1 Polyclonal Antibody (HF006014)

Name: Anti-Human BPNT1 Polyclonal Antibody
Brand: abinScience
SKU: HF006014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HF006014

Description

Anti-Human BPNT1 Polyclonal Antibody (HF006014) is a rabbit polyclonal antibody detecting BPNT1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human BPNT1 (Met1-Pro308).

Target

3'(2'), 5'-bisphosphate nucleotidase 1, 3.1.3.7, 3'-phosphoadenosine 5'-phosphate phosphatase, PAP phosphatase, Bisphosphate 3'-nucleotidase 1, BPntase 1, HsPIP, Inositol-polyphosphate 1-phosphatase, 3.1.3.57, BPNT1

Purification

Purified by antigen affinity column.

Accession

O95861

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

3'(2'),5'-bisphosphate nucleotidase 1 (BPNT1) is a ~33 kDa protein. Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate.

1. Yenush, L. et al. (2000) FEBS letters 467, 321-5. PMID: 10675562

Note

For research use only.

Images

References

Datasheet

Anti-Human BPNT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human BPNT1 Polyclonal Antibody (HF006014)

Overview

Images

References

Datasheet

SDS

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