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Anti-Human Calreticulin/CALR Recombinant Antibody (SAA0511) (HB190107)

Anti-Human Calreticulin/CALR Recombinant Antibody (SAA0511)
Anti-Human Calreticulin/CALR Recombinant Antibody (SAA0511)
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Overview
Catalog No.HB190107
Species reactivityHuman
ApplicationsFCM, WB
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0511
Clonality Monoclonal
Target Calreticulin, ERp60, CRTC, Calregulin, grp60, HACBP, Endoplasmic reticulum resident protein 60, CALR, CRP55
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P27797
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Calreticulin is a ~48 kDa protein. Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.

1. Nauseef, WM. et al. (1995) The Journal of biological chemistry 270, 4741-7. PMID: 7876246
2. Holaska, JM. et al. (2001) The Journal of cell biology 152, 127-40. PMID: 11149926
Note For research use only.
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  • Anti-Human Calreticulin/CALR Recombinant Antibody (SAA0511)

    SDS-PAGE

    SDS-PAGE for Anti-Human Calreticulin/CALR Antibody (SAA0511)

References
Formula
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Formula
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