Anti-Human CAVIN1 Polyclonal Antibody (HP645014)

Name: Anti-Human CAVIN1 Polyclonal Antibody
Brand: abinScience
SKU: HP645014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP645014

Description

Anti-Human CAVIN1 Polyclonal Antibody (HP645014) is a rabbit polyclonal antibody detecting CAVIN1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CAVIN1 (Leu43-Val153).

Target

Polymerase I and transcript release factor, CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF

Purification

Purified by antigen affinity column.

Accession

Q6NZI2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop.

1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712

2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225

3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human CAVIN1 polyclonal antibody at 1ug/mL on recombinant Human CAVIN1 (Catalog No. HP645012).

References

Datasheet