

| Catalog No. | HF733014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human CAVIN2 (Glu45-Lys156). | ||||||||
| Target | Caveolae-associated protein 2, SDPR, CAVIN2, Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O95810 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Caveolae-associated protein 2 (CAVIN2) is a ~47 kDa protein. Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. 1. Hansen, CG. et al. (2009) Nature cell biology 11, 807-14. PMID: 19525939 | ||||||||
| Note | For research use only. |
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