Anti-Human CBX2 Recombinant Antibody (SAA2130) (HC416013)

Name: Anti-Human CBX2 Recombinant Antibody (SAA2130)
Brand: abinScience
SKU: HC416013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC416013

Species reactivity

Human

Applications

ELISA, IF, IP

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG2a

Clone ID

SAA2130

Target

CBX2, Chromobox protein homolog 2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14781

RRID

Anti-Human CBX2 Antibody (SAA2130) (abinScience Cat# HC416013, RRID:AB_3729483)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Chromobox protein homolog 2 (CBX2) is a ~56 kDa protein. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). Plays a role in the lineage differentiation of the germ layers in embryonic development. Involved in sexual development, acting as activator of NR5A1 expression.

1. Vandamme, J. et al. (2011) Molecular & cellular proteomics : MCP 10, M110.002642. PMID: 21282530

2. Biason-Lauber, A. et al. (2009) American journal of human genetics 84, 658-63. PMID: 19361780

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CBX2 Antibody (SAA2130)

References

Datasheet

Anti-Human CBX2 Recombinant Antibody (SAA2130).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CBX2 Recombinant Antibody (SAA2130) (HC416013)

Overview

Images

References

Datasheet

SDS

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