

| Catalog No. | HT086014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CCL21/6Ckine (Ser24-Pro134). | ||||||||
| Target | C-C motif chemokine 21, SCYA21, Small-inducible cytokine A21, CCL21, Beta-chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O00585 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | C-C motif chemokine 21 (CCL21/6Ckine) is a ~14 kDa protein. Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-Human CCL21/6Ckine polyclonal antibody at 1ug/mL on recombinant Human CCL21/6Ckine (Catalog No. HT086012).


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