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Anti-Human CCL4/MIP-1-beta Recombinant Antibody (SAA0455) (HY327107)

Anti-Human CCL4/MIP-1-beta Recombinant Antibody (SAA0455)
Anti-Human CCL4/MIP-1-beta Recombinant Antibody (SAA0455)
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Overview
Catalog No.HY327107
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0455
Clonality Monoclonal
Target MIP-1-beta(1-69), MIP-1-beta, C-C motif chemokine 4, Protein H400, ACT-2, HC21, T-cell activation protein 2, Lymphocyte activation gene 1 protein, LAG-1, SIS-gamma, Small-inducible cytokine A4, G-26 T-lymphocyte-secreted protein, Macrophage inflammatory protein 1-beta, LAG1, PAT 744, CCL4, SCYA4, MIP1B
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P13236
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

C-C motif chemokine 4 (CCL4/MIP-1-beta) is a ~10 kDa protein. Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells.

Note For research use only.
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  • Anti-Human CCL4/MIP-1-beta Recombinant Antibody (SAA0455)

    SDS-PAGE

    SDS-PAGE for Anti-Human CCL4/MIP-1-beta Antibody (SAA0455)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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C₂ (Working Conc.)
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