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Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662) (HB666015)

Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662)
Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662)
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Overview
Catalog No.HB666015
Description
Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662) [1A662] (HB666015) is a mouse monoclonal antibody detecting CD11c in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A662
Clonality Monoclonal
Immunogen E. coli - derived recombinant human CD11c/ITGAX (Phe20-Pro1107).
Target Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p15095 alpha chain, Leukocyte adhesion receptor p15095, CD11c, ITGAX
Purification Protein A/G purified from cell culture supernatant.
Accession P20702
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Integrin alpha-X (CD11c/ITGAX) is a ~127 kDa protein. Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Functions as a receptor of the erythrocyte-specific adhesion molecule ICAM4 and mediates erythrophagocytosis.

1. Ihanus, E. et al. (2007) Blood 109, 802-10. PMID: 16985175
Note For research use only.
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  • Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD11c/ITGAX Monoclonal Antibody (1A662)

References
Formula
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