Anti-Human CD121b/IL1R2 Recombinant Antibody (SAA2093) (HB066033)

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Spec:

50ug
100ug
1mg

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Datasheet
SDS

Overview

Catalog No.

HB066033

Description

Anti-Human CD121b/IL1R2 Antibody (SAA2093) [SAA2093] (HB066033) is a human monoclonal antibody detecting CD121b in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Human

Isotype

IgG1, kappa

Clone ID

SAA2093

Clonality

Monoclonal

Target

sIL-1RII, IL-1RT-2, sIL-1R2, IL-1R-2, IL1RB, CD121 antigen-like family member B, CDw121b, IL-1RT2, Interleukin-1 receptor type II, mIL-1R2, CD121b, Interleukin-1 receptor type 2, mIL-1RII, IL-1R-beta, IL-1 type II receptor, Interleukin-1 receptor beta, IL1R2

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27930

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-1 receptor type 2 (CD121b/IL1R2) is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.

Note

For research use only.

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