

| Catalog No. | HV748117 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, lambda |
| Clone ID | 2G3 |
| Conjugation | FITC |
| Clonality | Monoclonal |
| Target | C-type lectin domain family 4 member K, CLEC4K, Langerin, CD207 |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| Accession | Q9UJ71 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | C-type lectin domain family 4 member K (CD207) is a ~36 kDa protein. Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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