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Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8) (HV997107)

Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)
Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)
Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)
Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)
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Overview
Catalog No.HV997107
Description
Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8) (HV997107) is a mouse monoclonal antibody detecting DC-SIGN/CD209 in FCM. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone ID2B8
Target CD209, DC-SIGN1, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, CD209 antigen, CLEC4L, DC-SIGN, C-type lectin domain family 4 member L
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9NNX6
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

CD209 antigen is a ~45 kDa protein. Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

Note For research use only.
Images
  • Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)

    SEC-HPLC

    SEC-HPLC detection for Anti-Human CD209 Antibody (2B8).

  • Anti-Human DC-SIGN/CD209 Recombinant Antibody (2B8)

    Bioactivity

    Detects CD209 in indirect ELISAs.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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