

| Catalog No. | HY541015 |
|---|---|
| Description |
Anti-Human CD23/FCER2 Monoclonal Antibody (1A503) [1A503] (HY541015) is a mouse monoclonal antibody detecting FCER2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, IHC, WB |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Clone ID | 1A503 |
| Immunogen | E. coli - derived recombinant human CD23/FCER2 (Asp48-Ser321). |
| Target | Low affinity immunoglobulin epsilon Fc receptor, BLAST-2, C-type lectin domain family 4 member J, Fc-epsilon-RII, Immunoglobulin E-binding factor, Lymphocyte IgE receptor, CD23, Low affinity immunoglobulin epsilon Fc receptor membrane-bound form, Low affinity immunoglobulin epsilon Fc receptor soluble form, FCER2 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P06734 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Low affinity immunoglobulin epsilon Fc receptor (CD23/FCER2) is a ~36 kDa protein. Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. 1. Pirron, U. et al. (1990) European journal of immunology 20, 1547-51. PMID: 2167225 2. Vouldoukis, I. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 7804-8. PMID: 7544003 |
| Note | For research use only. |

SDS-PAGE for Anti-Human CD23/FCER2 Monoclonal Antibody (1A503)




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