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Anti-Human CD265/TNFRSF11A Polyclonal Antibody (HV008014)

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Overview
Catalog No.HV008014
Description
Anti-Human CD265/TNFRSF11A Polyclonal Antibody (HV008014) is a rabbit polyclonal antibody detecting TNFRSF11A. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human CD265/TNFRSF11A (Ser36-Ser195).
Target CD265, ODFR, Osteoclast differentiation factor receptor, RANK, Receptor activator of NF-KB, TNFRSF11A, Tumor necrosis factor receptor superfamily member 11A
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Accession Q9Y6Q6
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Tumor necrosis factor receptor superfamily member 11A (CD265/TNFRSF11A) is a ~66 kDa protein. Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.

1. Nakagawa, N. et al. (1998) Biochemical and biophysical research communications 253, 395-400. PMID: 9878548
Note For research use only
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Formula
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Anti-Human CD265/TNFRSF11A Polyclonal Antibody

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