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Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (SSS-23) (HW338207)

Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (SSS-23)
Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (SSS-23)
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Overview
Catalog No.HW338207
Description
Anti-Human CD309/KDR/VEGFR-2 Antibody (SSS-23) [SSS-23] (HW338207) is a human monoclonal antibody detecting VEGFR-2 in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG1, kappa
Clone IDSSS-23
Clonality Monoclonal
Target FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P35968
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~151 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).

Note For research use only.
Images
  • Anti-Human VEGFR2/KDR/Flk-1 Recombinant Antibody (SSS-23)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD309/KDR/VEGFR-2 Antibody (SSS-23)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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