

| Catalog No. | HW338207 |
|---|---|
| Description |
Anti-Human CD309/KDR/VEGFR-2 Antibody (SSS-23) [SSS-23] (HW338207) is a human monoclonal antibody detecting VEGFR-2 in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | SSS-23 |
| Clonality | Monoclonal |
| Target | FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P35968 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~151 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza). |
| Note | For research use only. |

SDS-PAGE for Anti-Human CD309/KDR/VEGFR-2 Antibody (SSS-23)




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