Anti-Human CD312/ADGRE2 Polyclonal Antibody (HV987014)

Name: Anti-Human CD312/ADGRE2 Polyclonal Antibody
Brand: abinScience
SKU: HV987014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV987014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD312/ADGRE2 (Asn347-Ser509).

Target

EMR2, EGF-like module receptor 2, ADGRE2, EGF-like module-containing mucin-like hormone receptor-like 2, Adhesion G protein-coupled receptor E2, CD312

Purification

Purified by antigen affinity column.

Accession

Q9UHX3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Adhesion G protein-coupled receptor E2 (CD312/ADGRE2) is a ~90 kDa protein. Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation.

1. Boyden, SE. et al. (2016) The New England journal of medicine 374, 656-63. PMID: 26841242

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human CD312/ADGRE2 polyclonal antibody at 1ug/mL on recombinant Human CD312/ADGRE2 (Catalog No. HV987012).

References

Datasheet