Anti-Human CD349/FZD9 Recombinant Antibody (2933#) (HT468107)

Name: Anti-Human CD349/FZD9 Recombinant Antibody (2933#)
Brand: abinScience
SKU: HT468107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HT468107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	2933#
Clonality	Monoclonal
Target	FzE6, Frizzled-9, FZD9, FZD3, hFz9, CD349, Fz-9
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O00144
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Frizzled-9 (CD349/FZD9) is a ~64 kDa protein. Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. 1. Chailangkarn, T. et al. (2016) Nature 536, 338-43. PMID: 27509850
Note	For research use only.

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SDS-PAGE for Anti-Human CD349/FZD9 Antibody (2933#)

References

Datasheet

Anti-Human CD349/FZD9 Recombinant Antibody (2933#).pdf

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Anti-Human CD349/FZD9 Recombinant Antibody (2933#) (HT468107)

Overview

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Datasheet

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