



| Catalog No. | HF998107 |
|---|---|
| Description |
Anti-Human CD4 Antibody (SAA0002) [SAA0002] (HF998107) is a human monoclonal antibody detecting CD4 in FCM, FuncS. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM, FuncS |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | SAA0002 |
| Clonality | Monoclonal |
| Target | T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4, CD4 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P01730 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Note | For research use only. |

SEC-HPLC detection for Anti-Human CD4 Antibody (ABS1198).

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998011)
Lane 2: negative control




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