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Anti-Human CD40/TNFRSF5 Recombinant Antibody (4D11) (HB782107)

Anti-Human CD40/TNFRSF5 Recombinant Antibody (4D11)
Anti-Human CD40/TNFRSF5 Recombinant Antibody (4D11)
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Overview
Catalog No.HB782107
Species reactivityHuman
ApplicationsBlocking, FCM
Host speciesHuman
IsotypeIgG4, kappa
Clone ID4D11
Clonality Monoclonal
Target Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P25942
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Note For research use only.
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  • Anti-Human CD40/TNFRSF5 Recombinant Antibody (4D11)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD40/TNFRSF5 Antibody (4D11).

References
Formula
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