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Anti-Human CD41/CD61 Recombinant Antibody (PAC-1), FITC (HY355317)

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Overview
Catalog No.HY355317
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDPAC-1
ConjugationFITC
Clonality Monoclonal
Target CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A, PAC-1
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Associated products Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Purification Protein A/G purified from cell culture supernatant.
Accession P08514 & P05106
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage The antibody solution should be stored between 2 to 8°C in dark. DO NOT FREEZE!
References 1. Wang F, et al. A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts. Mol Oncol. 2014 Dec;8(8):1640-52. [HY355317]
2. Seervi M, et al. ERO1α-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1). Cell Death Dis. 2013 Dec 19;4:e968. [HY355317]
3. Putt KS, et al. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2006 Oct;2(10):543-50. [HY355317]
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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