Anti-Human CD57/B3GAT1 Monoclonal Antibody (1A589) (HV580025)

Name: Anti-Human CD57/B3GAT1 Monoclonal Antibody (1A589)
Brand: abinScience
SKU: HV580025
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HV580025
Description	Anti-Human CD57/B3GAT1 Monoclonal Antibody (1A589) [1A589] (HV580025) is a mouse monoclonal antibody detecting B3GAT1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A589
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human CD57/B3GAT1 (His25-Ile334).
Target	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, EC:2.4.1.135, Beta-13-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-13-glucuronyltransferase, GlcUAT-P, B3GAT1
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9P2W7
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (CD57/B3GAT1) is a ~38 kDa protein. Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Note	For research use only.