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Anti-Human P-Selectin/CD62P Recombinant Antibody (SelG1) (HB885107)

Anti-Human P-Selectin/CD62P Recombinant Antibody (SelG1)
Anti-Human P-Selectin/CD62P Recombinant Antibody (SelG1)
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Overview
Catalog No.HB885107
Description
Anti-Human CD62P/SELP Antibody (SelG1) [SelG1] (HB885107) is a human monoclonal antibody detecting CD62P in ELISA, FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesHuman
IsotypeIgG2, kappa
Clone IDSelG1
Clonality Monoclonal
Target Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRP
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P16109
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

P-selectin (CD62P/SELP) is a ~90 kDa protein. Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3).

1. Takada, YK. et al. (2023) Life science alliance 6. PMID: 37184585
Note For research use only.
Images
  • Anti-Human P-Selectin/CD62P Recombinant Antibody (SelG1)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD62P/SELP Antibody (SelG1).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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