

| Catalog No. | HY592107 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM, IHC, WB, IF |
| Host species | Human |
| Isotype | IgG1 |
| Clone ID | MOF11 |
| Clonality | Monoclonal |
| Target | Ocular melanoma-associated antigen, TSPAN30, CD63 antigen, LAMP-3, Tetraspanin-30, OMA81H, Lysosomal-associated membrane protein 3, Tspan-30, Granulophysin, MLA1, Melanoma-associated antigen ME491, CD63, RHC37601 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P08962 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | CD63 antigen (LAMP3) is a ~25 kDa protein. Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. |
| Note | For research use only. |

SEC-HPLC detection for Anti-Human CD63/LAMP3 Antibody (MOF11).




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