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Anti-Human CEACAM-5/CD66e Recombinant Antibody (RG7813), PE (HY546327)

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Overview
Catalog No.HY546327
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG1, kappa
Clone IDRG7813
ConjugationPE
Clonality Monoclonal
Target Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen
Endotoxin level Please contact with the lab for this information.
Associated products Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PE
Accession P06731
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933
2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050
3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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