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Anti-Human CD27 Ligand/TNFSF7/CD70 Recombinant Antibody (1F6), PerCP (HW717247)

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Overview
Catalog No.HW717247
Description
Anti-Human CD27 Ligand/TNFSF7/CD70 Recombinant Antibody (1F6), PerCP (HW717247) is a human monoclonal antibody detecting CD27 Ligand/TNFSF7/CD70 in FCM. Suitable for Human.
Highlights
  • ●PerCP Conjugated — Ready for direct detection without secondary antibody.
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone ID1F6
ConjugationPerCP
Target CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Associated products Human IgG1 kappa Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Accession P32970
Form Liquid
Storage buffer 0.01M PBS pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.

1. Izawa, K. et al. (2017) The Journal of experimental medicine 214, 73-89. PMID: 28011863
2. Abolhassani, H. et al. (2017) The Journal of experimental medicine 214, 91-106. PMID: 28011864
3. Goodwin, RG. et al. (1993) Cell 73, 447-56. PMID: 8387892
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
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