Anti-Human CD70 Recombinant Nanobody (SAA2049) (HW717013)

Name: Anti-Human CD70 Recombinant Nanobody (SAA2049)
Brand: abinScience
SKU: HW717013
Price: 126 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW717013

Description

Anti-Human CD70 Nanobody (SAA2049) [SAA2049] (HW717013) is a alpaca monoclonal antibody detecting CD70 in ELISA, FCM. Suitable for Human and Cynomolgus.

Highlights

●Flow Cytometry — Validated for flow cytometry applications.

Species reactivity

Human, Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Applications

ELISA, FCM

Host species

Alpaca

Isotype

VHH-8His-Cys-tag

Clone ID

SAA2049

Clonality

Monoclonal

Target

CD27 ligand, CD70, TNFSF7, CD27LG, CD27L, CD70 antigen, Tumor necrosis factor ligand superfamily member 7, CD27-L

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column

Accession

P32970

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

CD70 antigen is a ~21 kDa protein. Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.

1. Izawa, K. et al. (2017) The Journal of experimental medicine 214, 73-89. PMID: 28011863

2. Abolhassani, H. et al. (2017) The Journal of experimental medicine 214, 91-106. PMID: 28011864

3. Goodwin, RG. et al. (1993) Cell 73, 447-56. PMID: 8387892

Note

For research use only.

Images