Anti-Human Transferrin R/TfR Recombinant Antibody (128.1) (HY036507)

Name: Anti-Human Transferrin R/TfR Recombinant Antibody (128.1)
Brand: abinScience
SKU: HY036507
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HY036507
Description	Anti-Human Transferrin R/TfR Recombinant Antibody (128.1) (HY036507) is a mouse monoclonal antibody detecting Transferrin R/TfR in FCM. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	128.1
Target	CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P02786
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ch128.1
Background	Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. 1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738 2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human?CD71/TFRC Antibody (128.1)

References

Datasheet

Anti-Human Transferrin R/TfR Recombinant Antibody (128.1).pdf

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Anti-Human Transferrin R/TfR Recombinant Antibody (128.1) (HY036507)

Overview

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References

Datasheet

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