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Anti-Human CD71/TFRC Recombinant Antibody (OX-26) (HY036307)

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Anti-Human CD71/TFRC Recombinant Antibody (OX-26)

Anti-Human CD71/TFRC Recombinant Antibody (OX-26)

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Overview

Catalog No.	HY036307
Description	Anti-Human CD71/TFRC Antibody (OX-26) [OX-26] (HY036307) is a human monoclonal antibody detecting CD71 in FCM, IF, IHC (P), IP, WB. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM, IF, IHC (P), IP, WB
Host species	Human
Isotype	IgG1, kappa
Clone ID	OX-26
Clonality	Monoclonal
Target	Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, CD71, Tfrc, Trfr
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q62351
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Transferrin receptor protein 1 (CD71/TFRC) is a ~85 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Upon stimulation, positively regulates T and B cell proliferation through iron uptake. 1. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240 2. Yang, J. et al. (2024) The Journal of clinical investigation 134. PMID: 38625739
Note	For research use only.

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SDS-PAGE for Anti-Human CD71/TFRC Antibody (OX-26)

References

Datasheet

Anti-Human CD71/TFRC Recombinant Antibody (OX-26).pdf

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Anti-Human CD71/TFRC Recombinant Antibody (OX-26)