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Anti-Human CD79α/CD79A Monoclonal Antibody (1A575) (HY570025)

Anti-Human CD79α/CD79A Monoclonal Antibody (1A575)
Anti-Human CD79α/CD79A Monoclonal Antibody (1A575)
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Overview
Catalog No.HY570025
Description
Anti-Human CD79α/CD79A Monoclonal Antibody (1A575) [1A575] (HY570025) is a mouse monoclonal antibody detecting CD79a in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesMouse
IsotypeIgG
Clone ID1A575
Clonality Monoclonal
Immunogen E. coli - derived recombinant human CD79α/CD79A (Met35-Gly219).
Target B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A
Purification Protein A/G purified from cell culture supernatant.
Accession P11912
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

B-cell antigen receptor complex-associated protein alpha chain (CD79α/CD79A) is a ~25 kDa protein. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases.

Note For research use only.
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  • Anti-Human CD79α/CD79A Monoclonal Antibody (1A575)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD79α/CD79A Monoclonal Antibody (1A575)

References
Formula
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