Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), PE (HV631127)

Name: Anti-Human CD85j/LILRB1/ILT2 Recombinant Antibody (SAA0402), PE
Brand: abinScience
SKU: HV631127
Price: 290 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50T
100T

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HV631127
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0402
Conjugation	PE
Clonality	Monoclonal
Target	LIR1, Immunoglobulin-like transcript 2, MIR7, CD85 antigen-like family member J, Monocyte/macrophage immunoglobulin-like receptor 7, ILT-2, Leukocyte immunoglobulin-like receptor subfamily B member 1, LIR-1, CD85j, ILT2, LILRB1, MIR-7, Leukocyte immunoglobulin-like receptor 1
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
Accession	Q8NHL6
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Leukocyte immunoglobulin-like receptor subfamily B member 1 (CD85j/LILRB1) is a ~70 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. _x005F_x000D_ _x005F_x000D_ 1. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 _x005F_x000D_ _x005F_x000D_ 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 _x005F_x000D_ _x005F_x000D_ 3. Bellón, T. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 3351-9. PMID: 11907092 _x005F_x000D_ _x005F_x000D_ 4. Cosman, D. et al. (1997) Immunity 7, 273-82. PMID: 9285411 _x005F_x000D_ _x005F_x000D_ 5. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885 _x005F_x000D_ _x005F_x000D_ 6. Li, C. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5767-72. PMID: 19304799 _x005F_x000D_ _x005F_x000D_ 7. Fu, B. et al. (2017) Immunity 47, 1100-1113.e6. PMID: 29262349 _x005F_x000D_ _x005F_x000D_ 8. Naji, A. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 1536-46. PMID: 24453251
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.