

| Catalog No. | HV126127 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | 128-3 |
| Conjugation | PE |
| Clonality | Monoclonal |
| Target | CD85 antigen-like family member K, LIR-5, Leukocyte immunoglobulin-like receptor 5, ILT3, ILT-3, Immunoglobulin-like transcript 3, LILRB4, CD85k, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18, LIR5 |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE |
| Accession | Q8NHJ6 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85k/LILRB4) is a ~49 kDa protein. Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance. Receptor for FN1. Receptor for apolipoprotein APOE. Receptor for ALCAM/CD166. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. _x005F_x000D_ _x005F_x000D_1. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462 _x005F_x000D_
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2. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 _x005F_x000D_
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3. Deng, M. et al. (2018) Nature 562, 605-609. PMID: 30333625 _x005F_x000D_
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4. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 _x005F_x000D_
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5. Cella, M. et al. (1997) The Journal of experimental medicine 185, 1743-51. PMID: 9151699 _x005F_x000D_
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6. Lu, HK. et al. (2009) The Journal of biological chemistry 284, 34839-48. PMID: 19833736 _x005F_x000D_
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7. Kim-Schulze, S. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2790-8. PMID: 16493035 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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