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Anti-Human CECR2 IP Recombinant Antibody (SAA0196) (HP125013)

Anti-Human CECR2 IP Recombinant Antibody (SAA0196)
Anti-Human CECR2 IP Recombinant Antibody (SAA0196)
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Overview
Catalog No.HP125013
Species reactivityHuman
ApplicationsELISA, IF, IP
Host speciesMouse
IsotypeIgG2a
Clone IDSAA0196
Clonality Monoclonal
Target CECR2, Cat eye syndrome critical region protein 2, KIAA1740
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9BXF3
RRID Anti-Human CECR2 IP Antibody (SAA0196) (abinScience Cat# HP125013, RRID:AB_3729730)
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Chromatin remodeling regulator CECR2 is a ~164 kDa protein. Regulatory subunit of the ATP-dependent CERF-1 and CERF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. The complexes do not have the ability to slide mononucleosomes to the center of a DNA template. The CERF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the CERF-5 ISWI chromatin remodeling complex. Plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development. In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes.

1. Banting, GS. et al. (2005) Human molecular genetics 14, 513-24. PMID: 15640247
2. Filippakopoulos, P. et al. (2012) Cell 149, 214-31. PMID: 22464331
3. Flynn, EM. et al. (2015) Structure (London, England : 1993) 23, 1801-1814. PMID: 26365797
4. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535
5. Liu, L. et al. (2002) Genomics 79, 124-36. PMID: 11827465
Note For research use only.
Images
  • Anti-Human CECR2 IP Recombinant Antibody (SAA0196)

    SDS-PAGE

    SDS-PAGE for Anti-Human CECR2 IP Antibody (SAA0196).

References
Formula
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