Anti-Human CREPT Recombinant Antibody (3E10#) (HP069013)

Name: Anti-Human CREPT Recombinant Antibody (3E10#)
Brand: abinScience
SKU: HP069013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP069013

Species reactivity

Human

Applications

ELISA, IF, IHC, WB

Host species

Mouse

Isotype

IgG2a

Clone ID

3E10#

Clonality

Monoclonal

Target

RPRD1B, CREPT, Regulation of nuclear pre-mRNA domain-containing protein 1B, Cell cycle-related and expression-elevated protein in tumor

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NQG5

RRID

Anti-Human CREPT Antibody (3E10#) (abinScience Cat# HP069013, RRID:AB_3726982)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Regulation of nuclear pre-mRNA domain-containing protein 1B (CREPT/RPRD1B) is a ~36 kDa protein. Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CREPT Antibody (3E10#)

References

Datasheet

Anti-Human CREPT Recombinant Antibody (3E10#).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CREPT Recombinant Antibody (3E10#) (HP069013)

Overview

Images

References

Datasheet

SDS

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