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Anti-Human CRLS1 Polyclonal Antibody (HD659014)

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Overview
Catalog No.HD659014
Description
Anti-Human CRLS1 Polyclonal Antibody (HD659014) is a rabbit polyclonal antibody detecting CRLS1. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CRLS1 (Leu2-Thr108).
Target C20orf155, CLS, CLS1, CRLS1, Cardiolipin synthase (CMP-forming), EC:2.7.8.41, Protein GCD10 homolog
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9UJA2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Cardiolipin synthase (CMP-forming) (CRLS1) is a ~32 kDa protein. Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.

1. Lu, B. et al. (2006) Journal of lipid research 47, 1140-5. PMID: 16547353
2. Houtkooper, RH. et al. (2006) FEBS letters 580, 3059-64. PMID: 16678169
3. Chen, D. et al. (2006) The Biochemical journal 398, 169-76. PMID: 16716149
4. Lee, RG. et al. (2022) Human molecular genetics 31, 3597-3612. PMID: 35147173
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human CRLS1 Polyclonal Antibody

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