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Anti-Human CRNN Polyclonal Antibody (HP524014)

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Overview
Catalog No.HP524014
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human CRNN (Met1-Gly95).
Target SEP53, DRC1, Tumor-related protein, CRNN, 58 kDa heat shock protein, 53 kDa putative calcium-binding protein, C1orf10, PDRC1, 53 kDa squamous epithelial-induced stress protein, Squamous epithelial heat shock protein 53, Cornulin
Purification Purified by antigen affinity column.
Accession Q9UBG3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Cornulin (CRNN) is a ~53 kDa protein. Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. Regulates proliferation induced by pro-inflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways.

1. Li, C. et al. (2019) The Journal of investigative dermatology 139, 71-80. PMID: 30009832
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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