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Anti-Human CSDE1 Polyclonal Antibody (HF738014)

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Overview
Catalog No.HF738014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human CSDE1 (Ser172-Ser259).
Target UNR, Cold shock domain-containing protein E1, D1S155E, CSDE1, Protein UNR, KIAA0885, N-ras upstream gene protein, NRU
Purification Purified by antigen affinity column.
Accession O75534
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Cold shock domain-containing protein E1 (CSDE1) is a ~88 kDa protein. RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules.

1. Grosset, C. et al. (2000) Cell 103, 29-40. PMID: 11051545
2. Chang, TC. et al. (2004) Genes & development 18, 2010-23. PMID: 15314026
3. Youn, JY. et al. (2018) Molecular cell 69, 517-532.e11. PMID: 29395067
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human CSDE1 Polyclonal Antibody

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