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Anti-Human CYP2C18 Polyclonal Antibody (HC931014)

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Overview
Catalog No.HC931014
Description
Anti-Human CYP2C18 Polyclonal Antibody (HC931014) is a rabbit polyclonal antibody detecting CYP2C18. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CYP2C18 (Arg26-Val490).
Target CYP2C18, CYPIIC18, Cytochrome P450 2C18, Cytochrome P450-6b/29c, EC:1.14.14.1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P33260
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Cytochrome P450 2C18 (CYP2C18) is a ~55 kDa protein. A cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may modulate atRA signaling and clearance. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).

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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human CYP2C18 Polyclonal Antibody

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