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Anti-Human DAPK1 Polyclonal Antibody (HC207014)

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Overview
Catalog No.HC207014
Description
Anti-Human DAPK1 Polyclonal Antibody (HC207014) is a rabbit polyclonal antibody detecting DAPK1. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DAPK1 (Arg332-Arg679).
Target DAP kinase 1, DAPK, DAPK1, Death-associated protein kinase 1, EC:2.7.11.1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P53355
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Death-associated protein kinase 1 (DAPK1) is a ~160 kDa protein. Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells.

Note For research use only
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Formula
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Anti-Human DAPK1 Polyclonal Antibody

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