

| Catalog No. | HA492014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human DBNL Polyclonal Antibody (HA492014) is a rabbit polyclonal antibody detecting DBNL in ELISA, IHC, WB. Suitable for Rattus norvegicus, Bovine, Mus musculus, and Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human DBNL (Met1-Gly137). | ||||||||
| Target | DBNL | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UJU6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Alternate Names | Drebrin-like protein, Cervical SH3P7, Cervical mucin-associated protein, Drebrin-F, HPK1-interacting protein of 55 kDa, HIP-55, SH3 domain-containing protein 7, DBNL | ||||||||
| Background | Drebrin-like protein (DBNL) is a ~48 kDa protein. Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. | ||||||||
| Note | For research use only. |
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