

| Catalog No. | HX066014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human DEFB1 Polyclonal Antibody (HX066014) is a rabbit polyclonal antibody detecting DEFB1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human DEFB1 (Gly22-Lys68). | ||||||||
| Target | Beta-defensin 1, BD-1, hBD-1, Defensin, beta 1, DEFB1, BD1, HBD1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P60022 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Beta-defensin 1 (DEFB1) is a ~7 kDa protein. Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. 1. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 | ||||||||
| Note | For research use only. |
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