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Anti-Human DESI2 Polyclonal Antibody (HC211014)

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Overview
Catalog No.HC211014
Description
Anti-Human DESI2 Polyclonal Antibody (HC211014) is a rabbit polyclonal antibody detecting DESI2. Suitable for Mouse, Human, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DESI2 (Met1-Leu194).
Target C1orf121, DESI2, DeSI-2, Desumoylating isopeptidase 2, Deubiquitinase DESI2, EC:3.1.2.22, EC:3.4.19.12, FAM152A, PPPDE peptidase domain-containing protein 1, PPPDE1, Palmitoyl protein thioesterase DESI2, Protein FAM152A, S-depalmitoylase DESI2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9BSY9
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Deubiquitinase DESI2 is a ~21 kDa protein. Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).

1. Xie, X. et al. (2017) Biochemical and biophysical research communications 488, 291-296. PMID: 28483520
2. Luebben, AV. et al. (2022) Science advances 8, eabj8633. PMID: 35427157
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human DESI2 Polyclonal Antibody

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