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Anti-Human DHX8/DDX8 Polyclonal Antibody (HD594014)

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Overview
Catalog No.HD594014
Description
Anti-Human DHX8/DDX8 Polyclonal Antibody (HD594014) is a rabbit polyclonal antibody detecting DDX8. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DHX8/DDX8 (Val917-Arg1220).
Target ATP-dependent RNA helicase DHX8, DDX8, DEAH box protein 8, DHX8, EC:3.6.4.13, RNA helicase HRH1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q14562
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

ATP-dependent RNA helicase DHX8 (DDX8) is a ~139 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638
2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346
3. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770
4. Ohno, M. et al. (1996) Genes & development 10, 997-1007. PMID: 8608946
Note For research use only
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Datasheet
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Formula
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Working Solution
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Anti-Human DHX8/DDX8 Polyclonal Antibody

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