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Anti-Human DKK4 Polyclonal Antibody (HV359014)

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Anti-Human DKK4 Polyclonal Antibody
Anti-Human DKK4 Polyclonal Antibody
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Overview
Catalog No.HV359014
Description
Anti-Human DKK4 Polyclonal Antibody (HV359014) is a rabbit polyclonal antibody detecting Dickkopf-related protein 4; Dickkopf-4; Dkk-4; hDkk-4; Dickkopf-related protein 4 short form; DKK4. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DKK4 (Gln107-His212).
Target Dickkopf-related protein 4; Dickkopf-4; Dkk-4; hDkk-4; Dickkopf-related protein 4 short form; DKK4
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9UBT3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Dickkopf-related protein 4 (DKK4) is a ~24 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Note For research use only
Images
  • Anti-Human DKK4 Polyclonal Antibody

    Western blot

    Lane 1: K562 cell lysate

References
Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-Human DKK4 Polyclonal Antibody

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